A new Otogelin ENU mouse model for autosomal-recessive nonsyndromic moderate hearing impairment
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چکیده
منابع مشابه
A new Otogelin ENU mouse model for autosomal-recessive nonsyndromic moderate hearing impairment
Approximately 10 % of the population worldwide suffers from hearing loss (HL) and about 60 % of persons with early onset HL have hereditary hearing loss due to genetic mutations. Highly efficient mutagenesis in mice with the chemical mutagen, ethylnitrosourea (ENU), associated with relevant phenotypic tools represents a powerful approach in producing mouse models for hearing impairment. A benef...
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ژورنال
عنوان ژورنال: SpringerPlus
سال: 2015
ISSN: 2193-1801
DOI: 10.1186/s40064-015-1537-y